Five featured genes (EPHB3, DIP2B, RHEBL1, GALNT13, and SLC8A2) were identified upstream of hypoxia- and/or inflammation-related pathways mediated by microRNAs as potential biomarkers for sAMS. This evidence concerns the gene SLC8A2 and short stature-auditory canal atresia-mandibular hypoplasia-skeletal anomalies syndrome.