EIF4EBP1 and neoplasm: The 4E-binding protein 1 (4EBP1), belonging to a family of eukaryotic initiation factor 4E (eIF4E)-binding proteins, acts as a tumor suppressor by modulation the mammalian target of rapamycin (mTOR) pathway in some cancers, and may have additional oncogenic roles under other circumstances [17–19].