IGF1R and heart failure: Several additional loci have been implicated in other cardiovascular diseases such as heart failure (e.g., rs34163229 near SYNPO2L), cardiomyopathy (e.g., rs2255167 near TTN, rs3729989 near MYBPC3, rs143973349 near FLNC), and atrial fibrillation (e.g., rs6598541 near IGF1R), while others have been associated with cardiovascular risk factors such as blood pressure or diabetes.