Experimental studies link GPC1 to several types of cancers including pancreatic cancer [13], breast cancer [14], glioblastoma [15], esophageal squamous cell carcinoma (ESCC) [16], colorectal cancer [17], mesothelioma [18], prostate cancer [19], hepatocellular carcinoma [20] and cervical cancer [21] as few examples among many published studies. Here, GPC1 is linked to esophageal squamous cell carcinoma.