Additionally, we found that RHBDF2 expression was upregulated in both TP53 mutant and TP53 wild‐type HCC patients compared to normal controls, whereas RHBDF2 expression was significantly higher in TP53 mutant HCC patients than in TP53 wild‐type HCC patients (Fig. 1H). Here, TP53 is linked to hepatocellular carcinoma.