In one hand, PS results in a decrease in BDNF expression in the hippocampus of rat (Boersma et al., 2014; Weinstock, 2017) and on the other hand, it was shown that decreased hippocampal BDNF is involved in anxiety‐like behavior of rats (Saffarpour et al., 2019; Suliman et al., 2013). The gene discussed is BDNF; the disease is Anxiety.