We measured serum levels of two inflammatory markers, namely RANTES (regulated on activation, normal T cell expressed and secreted) and tumor necrosis factor‐alpha (TNF‐α), using Luminex assays in 109 preoperative DBS PD patients, 49 postoperative DBS PD patients, and 113 age‐ and sex‐matched controls. The gene discussed is SPARC; the disease is Parkinson disease.