A total of 1905 patients with minor stroke (defined by NIHSS ≤ 5) within a 4.5‐h time window were enrolled for subsequent analysis and the flowchart depicted the detailed reasons for exclusion (Figure 1), including TIA (n = 1184), pre‐stroke mRS ≥ 2 (n = 146), endovascular therapy including arterial thrombolysis and mechanical thrombectomy (n = 6), intravenous urokinase (n = 88), and no IV t‐PA due to absolute contraindications (n = 39). Here, PLAT is linked to stroke disorder.