This positive correlation between GCK and XBP1s expression was not detectable in the ND or IFG groups (R2 = 0.14, p = 0.25 in ND and R2 = 0.13, p = 0.30 in IFG, Figure 2D) but was present in T2D patients, in spite of their glycemic levels (R2 = 0.45, p = 0.048 in wT2D and R2 = 0.88, p = 0.017 in uT2D, Figure 2D). This evidence concerns the gene GCK and type 2 diabetes mellitus.