Moreover, sequencing studies carried out on AML and/or myelodysplastic syndromes (MDS) have found recurrent deleterious mutations in SWI/SNF genes including ARID2 [26], ARID1A and ARID1B [9], SMARCA2 [27], and SMARCA4 [10]. Here, SMARCA2 is linked to acute myeloid leukemia.