Indeed, the transcription of PRR genes, notably those of the Toll-like receptor (TLR) family are upregulated during sepsis, as well as pro-inflammatory cytokines such as tumor necrosis factor α (TNF-α), interleukins (IL)-1α, -1β, -6, and -12, and type-I interferons (IFN) [8, 9]. This evidence concerns the gene TNF and Sepsis.