BRD2 and neoplasm: Encouragingly, we found that the proportions of genes with significant HRs in both SMC-derived CRC (Fig. 6A) and TCGA-COAD (Fig. 6B) were significantly higher in NAT- than in tumor-derived transcriptomes; 53% NAT vs. 25% tumor for SMC-CRC samples (Fig. 6C), and 65% NAT vs. 31% tumor for TCGA-COAD samples (Fig. 6D).