LncRNA EGFR-AS1 derived from the reverse strand of lncRNA EGFR [7], it has been reported to regulate the expression of EGFR via heightening EGFR mRNA stability to active phosphatidylinositol-3 kinase (PI3K)/AKT pathway for the furtherance of the malignant progression of GC [8]. This evidence concerns the gene EGFR and gastric cancer.