High TUBA1C expression has been shown to be closely related to a poor prognosis in in various cancers, For example, the downregulation of TUBA1C inhibited the proliferation and migration of LUAD[13],hepatoma[17],and glioma[40] cells through cell cycle arrest, In addition, TUBA1C upregulates YAP expression and promotes aerobic glycolysis to promote breast cancer cell proliferation[14]. This evidence concerns the gene TUBA1C and cancer.