Results from the mass spectrometry (MS) analysis indicated the presence of several proteins, and we picked proteins that were strongly associated with cancer in differential bands,including TUBA1C, SERBP1, EEF1A1, CTSD, SMPD2, EIF4A1, and DNAJA4, out of which TUBA1C was the most abundant (Fig. 1D ) and the mass spectrum is obtained by separation according to the mass-to-charge ratio .(Fig. 1E). Here, SMPD2 is linked to cancer.