E2F1 and gastric cancer: Our further experiments show that TUBA1C promotes gastric cancer by accelerating the progression of the cell cycle from the G1 phase to the S phase and activating the expression of oncogene: Ki-67, E2F1 and PCNA(Fig. 7), and this is the first report showing that TUBA1C is a novel GC marker for early diagnosis, prognosis and progression.