F2 and COVID-19: Finally, several data have shown that in hospitalized COVID-19 patients, but not in asymptomatic/mild SARS-CoV-2 patients, the presence and increased levels of one or more serum auto-antibodies [including anti-phosphatidylserine/prothrombin (aPS/PT) IgM and IgG, anticardiolipin IgM and IgA, and anti-β2-glycoprotein 1 IgG positively correlated with increased severity of COVID-19 mortality [99–101], and, in vitro, to increased neutrophil extracellular traps (NETs) [101].