SMARCA4 and nasal cavity and paranasal sinus carcinoma: The differential diagnoses of NEC have expanded to include SWI/SNF complex-deficient sinonasal carcinomas, whether SMARCB1 or SMARCA4. These tumors predominantly affect adult males [59], typically arise in the paranasal sinuses (particularly the ethmoids) [59, 60], and frequently present at an advanced stage [59].