The first entity is the diffuse astrocytoma, MYB or MYBL1 altered, a low-grade tumor (WHO grade 1) with monomorphic glial cells and absent mitotic activity showing alterations of the genes for V-Myb avian myeloblastosis viral oncogene homolog (MYB) or V-Myb avian myeloblastosis viral oncogene homolog-like 1 (MYBL1) [36]. Here, MYB is linked to diffuse astrocytoma.