Consistent with these findings, unlike MYC/BCL2-driven B-ALL (VAL) and DLBCL (Karpas-422, SU-DHL-6, OCI-LY18) human cell lines, normal B cells of healthy donors did not express autocrine PRL and expressed the counteractive SFPRLRs (Fig. 5c, d). Here, BCL2 is linked to precursor B-cell acute lymphoblastic leukemia.