We found that the infiltrating abundance of the seven immune cells was significantly different between subtypes A and B. For example, the abundance of tumor-infiltrating activated memory CD4+ T cells was elevated in cluster A, while the abundance of Tregs and M2 macrophages was significantly higher in cluster B. Various antitumor biological effects of CD4+ T cells have been revealed in a previous study33. Here, CD4 is linked to neoplasm.