CDH2 and colorectal carcinoma: In addition, a recent study showed that exosomes from CRC cells containing high levels of functional A disintegrin and metalloproteinase 17 (ADAM17) increased the levels of N‐cadherin, vimentin, and snail, as well as E‐cadherin cleavage, promoting EMT in CRC cells, thus promoting CRC cell dissemination from the primary lesion to the liver.71