p62 phosphorylation was noticed only with ARP101 (Fig. 4D and Fig. 3B; hydroxamic acid) but not with the inactive version of ARP101 (Fig. 4D and Fig. 3B; carboxylic acid), suggesting specific activation of the noncanonical p62-Keap1-Nrf2 pathway by ARP101 during HCMV infection. This evidence concerns the gene NFE2L2 and cytomegalovirus infection.