Within the GRN mutation carriers, there seem to be two distinct groups, a nfvPPA group which overlaps to a large extent with sporadic nfvPPA, although at least in this cohort with fewer atypical parkinsonian motor features, and a PPA-NOS group, not neatly fitting into any of the canonical sporadic syndromes, with highly asymmetrical left hemisphere atrophy on brain imaging. The gene discussed is GRN; the disease is primary progressive aphasia.