HTN = hypertension; n = number of prescriptions; DHP-CCB = dihydropyridine-calcium channel blocker; RAS = renin-angiotensin system; ACEI = angiotensin‐converting enzyme inhibitor; ARB = angiotensin receptor blocker; TZD = thiazide; DM = diabetes mellitus; DLP = dyslipidemia; CKD = chronic kidney disease. This evidence concerns the gene REN and diabetes mellitus.