Given that four patients did not harbour a rare mutation, yet had lean NAFLD, we evaluated common variants associated with NAFLD and fibrosis (PNPLA3 rs738409:p.I148M, GCKR rs1260326:p.P446L, TM6SF2 rs58542926:C/T, and MBOAT7-TMC4 rs641738:C/T) and the protective variant HSD17B13 rs72613567:T/TA. This evidence concerns the gene GCKR and metabolic dysfunction-associated steatotic liver disease.