In this model of myocarditis, male BALB/c mice develop worse myocarditis with a dominant immune infiltrate of CD11b/complement receptor 3 (CR3)+ immune cells including neutrophils, macrophages, mast cells and dendritic cells, but there are no sex differences in cardiac viral replication (Figure 1) (40, 131, 132). Here, CRIPTO3 is linked to myocarditis.