GCG and Hyperglycemia: In recent work we have shown that the pharmacological activation of the glucagon-like peptide-1 (GLP1) receptor with agonists such as liraglutide and exendin 4 protect against olanzapine induced increases in glucagon and hyperglycemia, while antagonizing the GLP1 receptor potentiates the blood glucose response to olanzapine (Medak et al., 2020).