This ceramide-interacting protein, across quaternary membranes, can modulate the mTOR signaling pathway associated with autophagy (Dichlberger et al., 2021; Ji et al., 2022); LAPTM4B expression has been shown to be a poor prognostic marker in ovarian cancer (Yin et al., 2011). The gene discussed is LAPTM4B; the disease is ovarian carcinoma.