LAPTM4B and Familial prostate cancer: It would be worth noting that LAPTM4B-35, a protein encoded by LAPTM4B, is highly expressed in various solid tumors (Meng et al., 2016), and its overexpression is associated with poor prognosis in many malignancies, including ovarian, breast, cervical, and prostate cancers (Zhou et al., 2007; Qiao and Hu, 2015).