TP53 and neoplasm: Immunohistochemistry of the tumor cells were as follows: Muc-6 (+, focally), P16 (+, focally), P53 (20% medium intensity +), ER (+, focally), PR (-), CK7 (+++), CK20 (+, focally), Muc-2 (+, focally), Muc-5 (++), CDX-2 (+), SATB2 (-), Pax-8 (-), and the ki67 proliferative index was around 15% (Figure 3).