FBXO43 and neoplasm: We found that the FBXO43 expression level was positively associated with poor clinicopathological features, including UICC tumor stage (Pearson χ2 test, p=0.018), UICC stage (Pearson χ2 test, p=0.039), histological grade (Pearson χ2 test, p=0.010), vascular invasion (Pearson χ2 test, p=0.000), and adjacent inflammation (Pearson χ2 test, p=0.039) (Figures 1E–G; Table 1).