Although the involvement of GPVI in metastasis has rarely been studied (60–62), a few studies have reported that GPVI promotes experimental metastasis in Lewis lung carcinoma and melanoma models (34), and that GPVI inhibitor (revacept) and galectin-3 inhibitors prevent colon cancer metastasis in animal models (63). The gene discussed is GP6; the disease is malignant colon neoplasm.