PSMB8 and cancer: Furthermore, when these data were filtered by cancer type, individuals with the PSMB9 rs17587 SNP were more susceptible to gynecological cancers, while the PSMB8 rs2071543 SNP was associated with increased risk of gastrointestinal and gynecological cancers, especially in Asian populations [17,28]; the meta-analysis did not report results related to bladder cancer.