In addition, we compared our categorization to previously identified HCC molecular subgroups, including Boyault’s classification (G1–G6) (8), Chiang’s classification (Chr 7 polysomy class, CTNNB1 class, Interferon class, Proliferation class, and Unannotated class) (9), Hoshida’s classification (S1, S2, and S3) (10), and Désert’s classification (ECM/STEM, Periportal, and Perivenous type) (11). Here, CTNNB1 is linked to hepatocellular carcinoma.