Numerous studies have demonstrated the vital oncogenic role of AURKB (30), BIRC5 (31), KIF11 (32), PLK1 (33), PLK4 (34), RAD51 (35), TOP2A (36), TTK (37), and TUBB3 (38) in various cancers, including HCC. The gene discussed is BIRC5; the disease is hepatocellular carcinoma.