To this end, the transcription rate of eight typical IFN-stimulated genes (ISG) (i.e. IFIT1, IFI27, IFI44, IFI44L, ISG15, MX1, RSAD2 and SIGLEC1) was evaluated in MM cells at 12-h post-treatment by qPCR. This evidence concerns the gene ISG15 and Miyoshi myopathy.