Remarkably, the contribution of DPt to mount the TsKb20-CD8+ T cells response -depicted in Figure 2E as the ratio of TsKb20-CD8+ T cells in Sec22b+/+ (T cell response primed from both DPt and XPt) and TsKb20-CD8+ T lymphocytes in Sec22b−/− (T cell response primed only from DPt)- increases as the infection with T. cruzi progresses. This evidence concerns the gene SEC22B and infection.