Besides, antigen XPt is important in the development of the immune response against infection with other related parasites such as Toxoplasma gondii and Leishmania major, and Batf3−/− mice are extremely susceptible to infection with these parasites (Bertholet et al., 2006; Mashayekhi et al., 2011; Ashok et al., 2014; Martínez-López et al., 2015). The gene discussed is BATF3; the disease is infection.