Since FGF signaling is implicated in various stages of cochlear development (Ebeid and Huh, 2017), the identification of ESRP1 mutations in a patient with congenital hearing loss naturally led one group of researchers to hypothesize that ESRP1-mediated splicing of FGFRs is essential for hearing (Rohacek et al., 2017). This evidence concerns the gene ESRP1 and hearing loss disorder.