These variables were then included in multivariate stepwise backward Cox regression and revealed that gender (HR = 1.692, 95% CI: 1.33–2.16, P < 0.001), AFP (HR = 1.234, 95% CI: 1.02–1.49, P = 0.027), DCP (HR = 1.336, 95%CI: 1.16–1.54, P < 0.001), tumor number (HR = 1.223, 95% CI: 1.06–1.41, P = 0.006), tumor size (HR = 1.331, 95%CI: 1.16–1.53, P < 0.001), Fib (HR = 1.029, 95% CI: 1.01–1.05, P = 0.019), and APR (HR = 3.46, 95% CI: 2.02–10.77, P < 0.001) were independent predictors of RFS (Table 3). The gene discussed is ACE; the disease is neoplasm.