PIEZO1 and neoplasm: Moreover, compared with the sound pressure of 0.45 MPa for activating I92L-MscL in hippocampal neurons (Ye et al., 2018), 0.176 MPa or 0.6 MPa for activating PIEZO1 with microbubbles (Pan et al., 2018), the sound pressure of 0.053 MPa we used here proved to be effective in mice tumor suppression.