TBX5 variants in eight individuals from four unrelated families were also correlated with familial dilated cardiomyopathy and atrial septal aneurysm along with tricuspid atresia and pulmonary stenosis, which represented a novel phenotype that may have other underlying mechanisms (Shankar et al., 2017; Patterson et al., 2020). The gene discussed is TBX5; the disease is Pulmonic stenosis.