METTL3 and colorectal carcinoma: Previous study on the pathological role of m6A modification in CRC reported that METTL3, one of m6A regulators, directly induced m6A-glucose transporter 1 (GLUT1)-mammalian target of rapamycin complex 1 (mTORC1) axis to promote CRC initiation and progression (Chen et al., 2021).