As shown, compared with MCF-10A, the expression levels of GSDMC, GZMB and IL18 were upregulated, while TP63 was found with lower expression level in breast cancer cells SK-BR-3, BT-549, MCF-7, and MDA-MB-231 (Figures 3I–L, P < 0.05). This evidence concerns the gene GZMB and breast cancer.