Notably, IL1RA colocalised with five cardiometabolic traits (CRP, low density lipoprotein cholesterol, total cholesterol, triglycerides, and glucose), and coronary artery disease risk colocalised with MCSF and TRAIL (figure 4, online supplemental table 12; online supplemental figures 10a-s). The gene discussed is IL1RN; the disease is coronary artery disorder.