There are different forms of immune complex vasculitides (Table 1) (1): systemic and skin-limited variants (1) of IgA vasculitis (IgAV) (Figure 1), cryoglobulinemic vasculitis (CV), rheumatoid vasculitis (RV), lupus vasculitis (LE vasculitis), hypocomplementemic vasculitis (Figure 2), and serum sickness, as well as the provisionally defined forms of cutaneous IgM/IgG immune complex vasculitides and a recurrent macular vasculitis induced by hypergammaglobulinemia (Waldenström) (Figure 3) or by exertion or heat, or a, vasculitis in gammopathy other than cryoglobulinemic vasculitis (2, 3). The gene discussed is CD40LG; the disease is Henoch-Schoenlein purpura.