Here, seven sub-pathways, including cell cycle control, actin regulation, TGF-β, MAPK, PI3K-AKT, NF-κB, and the JAK-STAT signaling, were consistently mapped as targets of DEmiRNAs in the enriched KEGG pathways, which highlights them as the major cascades affected in PAS pathophysiology. Here, SOAT1 is linked to gonorrhea.