Two case analyses reported the correspondence and superiority of WF SS-OCTA relative to UWF FA in longitudinal assessment of retinal nonperfusion (RNP) in PDR, with higher detection rates in NP areas after anti-VEGF drug injection treatment (20), and provided important insights into the stability of retinal ischemia after PRP (21). The gene discussed is VEGFA; the disease is retinal ischemia.