VEGFA and retinal ischemia: Primary Outcome Measures: Total Number of Intravitreal Injections Over a 12 Month Period;VASecondary Outcome Measures: Retinal Ischemia; Foveal Avascular Zone; Adverse Events; Neovascularization of the Iris, Optic Nerve and Elsewhere; Central Foveal Outcome; Aqueous VEGF Levels;VF