IGF1 and lung cancer: The IVW method show no association between the IGF-1 and lung cancers (OR, 0.979, 95% CI, 0.849-1.129, P=0.773), as well as maximum likelihood, simple median, MR Egger and weighted median showed the consistent consequence (OR, 0.979, 95% CI, 0.857-1.101, P=0.736; OR, 0.992, 95% CI, 0.795-1.189, P=0.938; OR, 0.844, 95% CI, 0.601-1.187, P=0.332; OR, 0.949, 95% CI, 0.771-1.167, P=0.620, respectively).