Tumor PDHK1 expression tended to be smaller in the IMS-Prdx5 Clone 32 tumors than in Control A cells, but this was not statistically significant, possibly because of an increase in PDHK1 in tumor stromal cells, which would not have contained the IMS-Prdx5 protein and would still be responsive to the hypoxic tumor microenvironment. The gene discussed is PRDX5; the disease is neoplasm.