SELP and hyperlipidemia: Changes in the microenvironment, such as hyperlipidemia, can induce endothelial damage, increasing adhesion molecules, such as intercellular adhesion molecule‐1, vascular cell adhesion molecule‐1, and P‐selectin, and adhesion proteins, such as von Willebrand factor (vWF) and fibrin, thereby activating the adhesion of platelets to the damaged site [65].