This study showed lung deposition of immune complexes consisting of Ig and complement C3 in patients with DM who showed positive or negative findings for the anti-MDA5 antibody, indicating deposition of immune complexes in patients with DM who are positive for other myositis-specific antibodies for TIF1γ, Mi-2, SAE, and ARS. The gene discussed is IFIH1; the disease is dermatomyositis.