Moreover, the exosome-mediated transfer of miR-193a-3p, miR-210-3p, and miR-5100 (which are derived from hypoxic bone marrow-derived mesenchymal stem cells) has been shown to induce lung cancer cell invasion by modulating signal transducer and activator of transcription 3 (STAT3) signaling pathway [29]. This evidence concerns the gene STAT3 and lung cancer.