DNMT3A and acute lymphoblastic leukemia: When regarded as a continuous value, DNMT3A expression had a good predictive significance for relapse of B-ALL in children, with an area under curve (AUC) of 0.819 (95% CI: 0.686–0.952; P = 0.003), Fig. 3A), which indicated that DNMT3A expression could be a potential prognostic biomarker for ND B-ALL patients.