The peripheral blood samples of tumor-bearing E-/P-selectin KO mice contained a higher fraction of CD11b+ and CD11b+ Gr-1+ cells which were mainly related to the Gr-1Hi SCCInt (more differentiated neutrophils) population (Fig. 8B, see population A in Additional file 6: Fig. S6A also). The gene discussed is SELP; the disease is neoplasm.